The immense health benefits of curcumin, the bioactive component of turmeric that is widely used in Indian cuisine have been found in previous studies and now medical scientists in the US have found that it may be used to cure cancer in children.
The nanoparticles loaded with curcumin can offer a novel treatment
Neuroblastoma is the most common cancer in children younger than five years old and according to the scientists at Nemours Children's Hospital and the University of Central Florida (UCF). the nanoparticles loaded with curcumin can offer a novel treatment to target and destroy neuroblastoma tumour cells. In case of high-risk neuroblastoma, the survival may be poor as it may be resistant to traditional therapy. According to the experts, the high risk neuroblastoma is also associated with developmental delays, hearing loss, or other disabilities even after traditional treatments have ended.
The researchers linked curcumin to cerium oxide nanoparticles
The researchers linked curcumin to cerium oxide nanoparticles and tested the nano-curcumin formulation in cell lines of a high-risk form of neuroblastoma. “This formulation induced substantial cell death in neuroblastoma cells while producing no or only minor toxicity in healthy cells,” says their report in the journal Nanoscale. Studies have shown that curcumin has substantial anti-cancer ability, but what restricts its use in therapeutic applications is its low solubility and poor stability. According to a statement from UCF, “We are hopeful that in the future, nanoparticles can be utilised to personalise care to patients and reduce the late effects of therapy.”